The commentator appeared on Alan Colmes' radio show on Thursday, where she argued that her use of the word was not offensive because she was not discussing someone who had a mental disorder.
"Look, no one would refer to a Down Syndrome child, someone with an actual mental handicap, by saying 'retard,'" Ann Coulter said, according to Daily Caller. "Where do you think the words 'imbecile,' 'idiot,' 'moron,' 'cretin' come from? These were all technical terms at one time. 'Retard' had been used colloquially to just mean 'loser' for 30 years," she continued. "But no, no - these aggressive victims have to come out and tell you what words to use."
Ann Coulter first used "retard" on Monday night during the final presidential debate between Obama and Republican candidate Mitt Romney.
"I highly approve of Romney's decision to be kind and gentle to the retard," she tweeted at the time.
The following day, she tweeted the word again, writing, "Obama: "Stage 3 Romneysia" - because cancer references are HILARIOUS. If he's "the smartest guy in the room" it must be one retarded room."
Since then, the conservative has faced numerous critics, but Ann Coulter said on Thursday that she does not care about them.
"Oh, screw them," she said. "That's what they feel I do? I feel they're being authoritarian bullying victims."
"This is the other thing about liberal victims - they always claim, like the Jersey Girls, to speak on behalf of all the victims of 9/11," she continued. "No you don't, you big bullies."
One of her most vocal critics was a Special Olympian named John Franklin Stephens. Stephens, who has Down Syndrome, wrote an open letter to Coulter earlier this week.
"After I saw your tweet, I realized you just wanted to belittle the President by linking him to people like me," Stephens wrote. "You assumed that people would understand and accept that being linked to someone like me is an insult and you assumed you could get away with it and still appear on TV."
"Well, Ms. Coulter, you, and society, need to learn that being compared to people like me should be considered a badge of honor," he continued.
Coulter responded to Stephens during the interview.
"I was not making a joke about Special Olympics the way our president did, by the way," she said. "It would be one thing if I said in my tweet a joke about Special Olympics, a joke about Down Syndrome. No one would call someone with Down Syndrome 'retard.' I call you a 'retard.'"
Coulter was referring to Obama's comments on "The Tonight Show" in 2009. The president told host Jay Leno that he bowled a 129 at the alley in the White House.
"It was like the Special Olympics or something," he said at the time.
The president has since apologized for that remark.
To hear the audio of Coulter's interview, click the video below, courtesy of Mediaite.
To see our previous coverage of this incident, click the links below.